Interestingly, major pilins undergo post-translational modifications in these regions (Fig. 5A), most often addition of glycans, although phosphorylcholine, phosphoethanolamine and phosphoglycerol, have also been described (Forest et al., 1999; Hegge et al., 2004; Gault et al., 2013).
Instead, traditional proficiency testing material (PTM) is generally made from animal plasma or outdated human plasma from blood banks, often with addition of preservatives, stabilizers, and other additives.
Kumquats can be made into marmalades and jams, of course, their bitter edges softened by sugar and often the addition of tangerines or mandarin oranges.
The physical and chemical conditions leading to production of the different products types is difficult to define precisely from the literature as a range of cultivation modes have been employed and often the addition of complex medium components complicate accurate interpretation of cause and effect.
While a movie needs a strong story and distinct characters to be good, it's often the addition of a sense of time and place that makes a movie great.
Previous studies of H2 production of hydrogenase mutants have been based on harvested cell concentrates, often with addition of 100 mM formate to increase FHL activity, although such high formate concentration is incompatible with growth [9], [25], [33].
Finally patients typically accrue increasing medications, with management often comprising addition of new medication, with existing (or previously added) ones seldom discontinued for fear of causing destabilisation.
The separation of the parent drug and polar metabolites in one chromatographic run usually requires the use of gradient elution and often the addition of ionic modifiers into the mobile phase to increase the retention of polar conjugates [ 30].
Analysis of precisely controlled post-translational modifications of proteins, often with addition of only a small functionality (e.g., single phosphorylation), which can change activity of a kinase up to 10 times, is a big challenge for analytical chemistry at present.
What is the often-overpaid addition of a designated hitter if not implants for a baseball team?
In comparison to Drosha, which often requires the addition of accessory factors to promote processing, regulation of miRNAs at the Dicer step often involves inhibition of Dicer activity.
