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Homozygous offspring, identified by PCR and immunofluorescence, were able to implant but were arrested or retarded in growth.
Male and female chimaeric offspring, identified by the presence of agouti coat colour, were then bred to C57BL/6J mice to assay for germ-line transmission.
Includes only families with more than 1 offspring identified.
There were two individuals who had spawned in consecutive years and had offspring identified (i.e., multiple spawners).
For paternal links, "dummy" sires were created to represent half-sibships between groups of offspring identified by COLONY to have a common (unsampled) father.
We studied well-phenotyped FGR offspring identified in utero according to customized fetal growth scales in otherwise healthy mothers and in the absence of other fetal disease.
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Now both they and their visiting offspring identify with Wilmington.
Male chimeric offspring were bred with C57BL/6 females and RIαB agouti offspring were identified by Southern blot and PCR analyses as described above.
To take the relatedness of offspring subjects into account, family clusters of offspring control pairs with related offspring were identified, and robust variance estimates based on the clustering were obtained.
No homozygous offspring were identified.
High-risk offspring were identified from families in which one parent had confirmed bipolar disorder.
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