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Migration may be a cyclical phenomenon, but it's not good when a nature documentary's story lines blur together into a clichéd cycle of drying river, fighting males, skittish females, spindly offspring, heart-tugging death (cue the vultures), heroic struggle and eventual arrival (cue the triumphal music).
Cardiomyocytes of offspring hearts were more vulnerable to PHT administration compared with the mother animals.
Offspring hearts from all time points were fixed in 10% NBF, processed, and embedded in paraffin.
Maternal diabetes mellitus is associated with an increased risk of offspring congenital heart defects (CHD); however, the causal mechanism is poorly understood.
In a first time, these studies evidenced an association with chronic diseases in adult life in the offspring (coronary heart disease, atherogenic lipid profile, obesity, raised levels of plasma fibrinogen, and decreased levels of factor VII), strongly related to the timing in gestation of exposure to famine [ 158, 159].
When the mutants mate, half the offspring have hearts on the left and half on the right.
After Gabriel's love for "the offspring of my heart" is sullied by misgivings, the book opens out into a mystery studded with elegant twists and turns.
Participants for this study were part of the Framingham Heart Study MDCT Study, a substudy of the population-based Framingham Heart Offspring and Third Generation study cohorts.
In addition, some organ weights differed between the sexes in HFD-fed offspring, with absolute heart and kidney weights (in both exposure groups) being lower in female pups than in the age-/exposure-matched male offspring.
Smedts et al., 23 in a case control study of offspring with congenital heart disease, found that periconceptual use of vitamin E supplements with high dietary intake of the same vitamin was associated with up to nine-fold increase in the risk of congenital heart disease.
To examine the potential association between maternal use of ACE inhibitors during the first trimester and the risk of malformations in offspring, especially congenital heart defects and neural tube defects, we conducted a large, population based, cohort study based on information from more than 465 000 mother-infant pairs from 1995 to 2008 in the Kaiser Permanente Northern California system.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com