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A rapid increase in the manufacture of reinforcement-grade boron-containing fiberglass in Asia, has offset the development of boron-free reinforcement-grade fiberglass in Europe and the USA.
Although ectopic overproduction of adiponectin can reduce food intake in high-fat-fed rats and offset the development of diet-induced obesity (Shklyaev et al., 2003), food intake in adiponectin knockout mice is no different from that seen in wild-type littermates (Maeda et al., 2002).
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However, the success of these treatments is offset by the development of drug resistance and by toxic side-effects on healthy cells and tissues.
These accruals of savings over time offset the initial development costs, emphasizing the importance of the intervention's duration of effect in understanding the relation of costs to the interventions overall cost effectiveness.
This data can be useful to develop strategies to offset the impacts of urban development (e.g., designs and patterns resulting in variable impervious areas) and management (e.g., fertilizer use, landscaping practices) on NO3 N and PO4 P transport in urban residential catchments.
[For more on this technology, see "Biochar: Carbon Mitigation from the Ground Up," p. A70 this issue.] The imperative, stresses Lewis Milford, president of the Clean Energy Group, a Vermont firm that seeks to accelerate the renewable energy market, is that any focus on offsets not slow the development of breakthrough technologies needed to reverse climate change quickly.
However, whereas improved income should increase rural residents' ability to pay, the rising cost of care in rural areas may offset the benefits of socioeconomic development.
Diana Weir, executive vice president of the Long Island Housing Partnership, mentioned that to offset the costs of "smart growth" developments like those near train stations, there was some help to be had from a $25 million state bond floated in May.
"Yes, we're in this to make money -- not just out of the graciousness of our hearts," the builder said, explaining that many of the life-style extras at BelleFair -- like the 20,000-square-foot meeting house and the store stocked with licorice and "sweet and sours" -- also help offset the harsh reality of the development's noisy next-door neighbor: the Westchester County Airiport.
Sales of Alpha systems aren't likely to ever be robust enough to offset the huge expense of development, marketing and maintenance.
But while Alpha was universally hailed as a technical marvel, Digital never managed to market it well enough to achieve large enough volumes, which would have offset the huge costs of development and manufacturing.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com