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Even in the presence of severe insulin resistance, a perfectly normal β-cell is capable of secreting sufficient amounts of insulin to offset the defect in insulin action.
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For example, using HDACi to sensitize tumors to radiation could lead to secondary mutations., On the other hand, using HDACi to offset the transcriptional defects in Huntington's disease may have the additional benefit of reducing somatic expansions at the HD gene and thereby slowing disease progression.
The advisory committee to the Food and Drug Administration voted 20 to 2 that the benefits from the weight loss provided by the drug, Qnexa, more than offset the potential risks of heart problems and birth defects.
Black offset the leaves.
"Emotional rebellions offset the power-loving side".
Will one offset the other?
Helps offset the high rate.
Won't transaction costs offset the tax advantages?
There are ways to offset the costs.
Does that offset the weekend?
The sugar will offset the salty flavor.
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