Because rFVIIa is not approved for any of the indications discussed in this publication, the patient's next of kin should be informed that rFVIIa is being used outside the currently approved indications (off-label use).
Another continuing debate is whether Ryan's cussing and ruminations and off-the-field antics are an indication of an organizational lack of discipline.
Off-label: Off-label by indication; the medication was prescribed for other non-recommended indications or there was no information in the medical record of the patient having neither asthma nor COPD.
"I don't think the fact that a drug is taken off the market is an indication that it should not have been approved," said Dr. John Jenkins, director of a drug evaluation office for the Food and Drug Administration.
No one likes being called odd, even "non-racists", but UKIP leader Nigel Farage brushed off the remarks as an indication of "how disconnected [David Cameron] is".
That morning, we were told that a soldier who we would soon learn was Bowe Bergdahl had apparently walked off the base, and all indications were that he had done it voluntarily.
On days when it appeared that the Fed might be preparing to pull back on the stimulus, stocks have generally sold off, while indications that the Fed might continue on with the stimulus have led markets up.
All bets on the match were duly called off – an indication of how completely things had got out of hand".
Several large multicenter observational case series have documented the safety of high-dose daptomycin, to include the treatment of VRE bacteremia which is also an off label indication for its use [ 60– 63].
The FDA noted that no products have been approved for the indication, and suggested that the committee consider whether a number of products that are used off-label for the indication should be considered "available therapy".
