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On and off pathway translocation mechanisms were modeled.
However, the generality of ON and OFF pathway asymmetries has not been tested.
Signal-to-noise ratios were weaker in the ASD group, particularly for the OFF pathway.
It was the first time the grieving parents had visited the unremarkable fenced off pathway, behind an auto repair shop and next to a busy highway, where their son died three months ago.
All transcription pauses are thought to be off pathway (a non-obligatory) events (Herbert et al, 2008; Landick, 2009).
Similar(55)
Both the on-pathway and off-pathway I120Q intermediates show structure in β1-β3, whish is also strikingly consistent with kinetic folding experiments of αTS.
The trade-off pathway most often observed reinforces the chosen visualization in terms of policy measures.
Politicians need not fear looking soft on border controls if they agree with a one-off pathway into citizenship for long-term migrants.
Mutations and off-pathway aggregation of proteins.
Alternative models for pausing invoke blockade events that precede translocation (on-pathway), enzyme backtracking (off-pathway), or isomerization to a nonbacktracked, elemental pause state (off-pathway).
Compartmentalization can prevent escape of volatile or toxic intermediates, prevent off-pathway reactions, and create private cofactor pools.
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