Its snubs of Hispanic and African-American voters kissed off essential swing states in the Sun Belt and moderate swing voters farther north.
And companies are increasingly factoring in the rising cost of shipping goods across oceans, and the risk that natural disasters or geopolitical shocks could cut off essential supplies.
And Cypriots feel they have been blackmailed by the European Central Bank's vows to cut off essential low-interest loans to the country's banks, unless Cyprus quickly agrees to Europe's bailout terms, he said.
The West knows the cost of wars at this point — not just in lives and treasure, but also in the skewing of the national debate in ways that put off essential decisions on education, energy and infrastructure.
But given that the royal commission into Victoria's Black Saturday fire disaster in Victoria did attribute blame for five of the most lethal fires to eroded maintenance standards in the wake of cost-cutting privatisation "efficiencies", questions about the wisdom of selling off essential services like electricity – in South Australia or anywhere else – are timely and valid.
These four polyamides turned off essential genes that help the bacteria duplicate their genomes and make key proteins, according to results from another Genesoft team headed by James Ge.
They have learned how to turn on and off essential genes and how to transform embryonic stem cells into retinal cells, which can be transplanted into mice to restore vision.
While its original intention was to eliminate illegal, unscrupulous businesses, "Choke Point" is adversely impacting legal, licensed companies, cutting off essential banking services to these businesses.
The riots are not only violent but they also end up blocking the city's streets and cutting off essential services like water distribution and sewage removal.
Obviously, he needs them to get back and forth from town with his year's furs in the summer, but he also relies on a couple intermittent visits from pilots in the fall to drop off essential supplies for the winter, like snowmachine fuel and craisins.
