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This close functional and molecular integration of the immune and metabolic systems is emerging as a crucial homeostatic mechanism, the dysfunction of which underlies many chronic metabolic diseases, including type 2 diabetes and atherosclerosis.
According to him, respect expresses the foundation of morality as such, because the "contractualist ideal of acting in accord with principles that others (similarly motivated) could not reasonably reject is meant to characterize the relations with others the value and appeal of which underlies our reasons to do what morality requires.
Lis1, a mutation of which underlies human lissencephaly, is a regulatory protein of the microtubule motor dynein, and is highly conserved from human to Drosophila.
We have identified several new members of the MID1/α4 complex, dysfunction of which underlies the pathogenesis of OS.
The close functional and molecular integration of the immune and metabolic systems is emerging as a crucial homeostatic mechanism, the dysfunction of which underlies many chronic metabolic diseases, including type 2 diabetes and atherosclerosis.
This detoxification machinery in insects has been mainly attributed to three enzyme systems, namely cytochrome P450s, esterases, and glutathione S-transferases (GSTs), the up-regulation of which underlies the development of insecticide resistance in many insect species.
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Unlike previously described sensorineural deafness genes, all of which underlie cochlear cell pathologies, DFNB59 is the first human gene implicated in nonsyndromic deafness due to a neuronal defect.
The next 5 years will see the determination of which underlying variables will be most important to quantifying vaccine efficacy.
Over the past nine months, we have assisted with the curation of a variety of datasets deposited within the DDR, many of which underlie journal publications.
Study of the role of these factors in the context of various cellular processes, alterations of which, underlie the pathogenesis of several diseases is an area worthy of investigation.
This is true regardless of which underlying clustering approach is used.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com