Sentence examples for of which underlie from inspiring English sources

Study of the role of these factors in the context of various cellular processes, alterations of which, underlie the pathogenesis of several diseases is an area worthy of investigation.

Humans have five RecQ homologs, defects in three of which underlie cancer predisposition syndromes and any of which may be mutated in sporadic cancers (Monnat 2010).

In potato, NBS-LRR genes from a BAC library and 38 resistance loci co-localized with TIR-NBS-LRRs, most of which underlie QTL [ 13].

MM as well as most cancers has a striking genetic instability, which in turn leads to accumulation of mutational changes, some of which underlie tumor progression, drug resistance, and metastasis [ 19, 38].

OSA can lead to or has been associated with GERD, asthma symptoms and upper respiratory complaints, all of which underlie the "pathogenic triad" leading to more than 95% of chronic cough [ 18].

The Latin America and the Caribbean region is facing a number of challenges, including the recent economic slowdown, the more than 130 million chronically poor people, pervasive inequality, high levels of violence and recurrent natural disasters, all of which underlie the humanitarian situation, undermine substantive development gains and reinforce persistent poverty.

The next 5 years will see the determination of which underlying variables will be most important to quantifying vaccine efficacy.

According to him, respect expresses the foundation of morality as such, because the "contractualist ideal of acting in accord with principles that others (similarly motivated) could not reasonably reject is meant to characterize the relations with others the value and appeal of which underlies our reasons to do what morality requires.

Lis1, a mutation of which underlies human lissencephaly, is a regulatory protein of the microtubule motor dynein, and is highly conserved from human to Drosophila.

This is true regardless of which underlying clustering approach is used.

We have identified several new members of the MID1/α4 complex, dysfunction of which underlies the pathogenesis of OS.