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Defining value as outcomes relative to costs only begs the question of which outcomes matter and how they should be measured.
A condition for multiplex polymerase chain reactions (PCRs) of which outcomes sensitively indicate the actual annealing temperature of thermal cycling is reported.
However, there was a high level of heterogeneity of perception between and within stakeholder groups (implementers and target communities), both in terms of which outcomes were most important and how well they had been achieved.
Non-uniform outcome selection can make it difficult to design, interpret, and meta-analyse clinical trials [15], [16], [39], [40], and so a few collaborations have begun to address the problems of which outcomes to measure in clinical trials of a variety of paediatric and adult conditions [9], [15].
We would note, however, the relative value and importance of different outcomes was not identified in terms of the frequency of which outcomes were mentioned.
This field of research could benefit from stronger evaluative designs and knowledge of which outcomes common to a range of networks (ie other than disease-specific patient health outcomes) should be measured.
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More recently, some consequentialists have added some notion of fairness (Broome 1991, 192 200) or desert (Feldman 1997, 154 74) to their test of which outcome is best.
Being stuck somewhere between those two places and totally unsure of which outcome you'll be left with can be overwhelming, alarming, and confusing.
For genetic risk prediction studies, the objectives should specify which models are investigated for the prediction of which outcome in which population and setting.
This raises the question of which outcome we then 'believe' if there are gains in one and losses in the other.
Thus, we implicitly assumed that both probabilities are linearly related, so that the RR is identical irrespective of which outcome is considered.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com