He describes the scandals that touched the Grant administration, the worst of which implicated William Belknap, the secretary of war, who took a kickback from a contractor running a military trading post.
Progress in cardiovascular diseases (CVD) has been particularly impressive, with genome-wide association studies (GWAS) leading to the identification of ∼160 loci associated with CVD and its risk factors, many of which implicate new biological pathways.
Here we used two studies, both of which implicated novel susceptibility genes for Crohn's disease, as a basis for identifying biological pathways associated with the disease.
A number of studies have described agents that sensitize one or more breast cancer subtypes to TRAIL, the majority of which implicate components of the apoptosis regulatory machinery as the underlying causes of sensitization [ 22- 35].
Taken together, our data indicate Kirrel3 is present at early axon dendrite contacts, localizes at or near synapses, and is a bona fide homophilic adhesion molecule, all of which implicate Kirrel3 in synapse development.
This alteration in a balance between the impact of hedonically salient, compared with neutral, outcomes might underlie a range of phenomena, including the bias in salience attribution to cues observed in the depressive state, addiction (Diekhof et al. 2008) and Tourette syndrome (Gilbert et al. 2006) all of which implicate dysfunction in dopaminergic pathways.
The most frequently mentioned medication classes associated with 182 survey-described ADRs in the past 4 weeks that cited one or more drugs (216 drug citations) were antibiotics (38%, 83/216), antiretroviral agents (23%, 49/216), antimalarials (15%, 33/216, 15 of which implicated quinine), analgaesics (9%, 19/216) and others (15%, 32/216).
Importantly, Salazar et al. [ 96] also showed that DMT1+IRE was elevated in the SN of PD patients, which implicates overexpression of this protein in iron accumulation in PD.
Another German researcher and clinician, Dr Mazda Adli, is a keen advocate of one theory, which implicates that most paradoxical urban mixture: loneliness in crowds.
LPC-treatment of the roots resulted in enhanced freezing tolerance in the aerial parts of the plant, which implicates LPC in inducing systemic metabolic responses.
