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Considering the total number of M-SNPs in each village, we identified a group of village specific M-SNPs that range from the highest values in Urzulei and Talana (5.04% and 4.33% respectively) to the lowest in Seui and Loceri (1.85% and 1.45% respectively).
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Analyses were disaggregated by the location of the respondents in order to obtain estimates of village-specific maternal deaths, i.e. respondent location was used as a proxy for the location of the sister.
This interpretation gains further support in subsequent analyses where the presence of the village-specific ancestry component was found to be highly correlated with both extended LD range and elevated levels of gROH (Supplementary Figure 7; see below).
For further analyses, the village populations were split into sub-populations (referred as GS and IS) based on the prevalence of the village-specific ancestry component (described in Materials and Methods section) and considered as independent populations to more accurately represent the genetic diversity within FVG villages.
WASMO uses participatory planning to assess villages' specific water needs.
While we were unable to make village-specific estimates of sporozoite prevalence, the overall mean reported here at high bednet coverage is substantially lower than previous reports for both vector species in both villages previously surveyed.
Village-specific analyses showed that more than 15% of the sisters identified from the villages of Makana, Bafing-Makana, Koba, Fangalakouta and Kologon had suffered a pregnancy related death (Table 2).
The TRDS-2000 provides annual dose estimates based primarily on age- and village-specific group means that were individualised to account for the periods of residence in contaminated villages.
c Separate village-specific sporozoite infection prevalence estimates could not be obtained from the recent surveys because of lack of sufficient samples from each village.
For example, the median village well water level may to some degree misrepresent the village-specific exposure because it ignores the marked variability in well water arsenic measures for a number of villages.
These two estimates were highly correlated with the village-specific ancestral components (Supplementary Figure 7) and thus it is probably the decreased diversity because of small Ne in the subsets of villages that is behind the striking structure.
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