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Appendage morphogenesis is regulated by the concerted activities of various signalling pathways, including Wnt.
The formation of a hierarchical network of vessels requires the coordinated interplay of various signalling pathways.
Thus, phosphorylation of intracellular tyrosine and serine residues or constitutive and inducible protein-protein interactions have been implicated in the initiation or modification of various signalling pathways.
These proteins thus have the capacity to interact with lipid and protein moieties at the membranes, contributing to stress adaptation via regulation of various signalling pathways [ 88].
3 The NF-κB family of transcription factors regulates the activities of various signalling pathways, and its members are considered key regulators in inflammation, oncogenesis and apoptosis.
Alk kinase is upstream of various signalling pathways such as the MAPK ERK, the Jak STAT and the PI3K Akt pathway [ 103].
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Eliminating DAB2 expression may contribute to disruption of various signalling pathway in NPC.
Subsequently, the cells were treated with or without TNF-α, with or without pretreatment with inhibitors of various signaling pathways.
Genetic screens have been proven powerful for the identification of components of various signaling pathways.
In MM, the balanced homeostasis between these BM compartments is disrupted and supports MM cell proliferation, survival, migration, and drug resistance via activation of various signaling pathways.
These data suggest that Rac1b expression acts as a modulator or transducer of various signaling pathways that lead to NFT formation and membrane dysfunction in a subgroup of CBF NB neurons in AD.
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