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Any uncertainties, such as slight differences of unknown relevance to clinical performance, should be addressed via comparative clinical data.
M5 included five more Pfam domains of unknown relevance which are interesting candidates for novel functional activities (Table 3).
Apart from the caucasian founder mutation E265X, a missense change of unknown relevance, R400P, was observed in our study samples.
We used reliable and valid metrics that assessed local constructs of mental health rather than translating a "western" model of unknown relevance in Gulu [ 18, 22].
Hypothetical unknown proteins (including the MbnC replacement in Group V operons) are present in several operons, and a range of proteins of unknown relevance, including several varieties of known copper-related proteins, appear in a few operons only.
Besides clear pathogenic mutations (nonsense mutations or insertions and deletions leading to truncated proteins), many unclassified variants also exist, for example, missense mutations of unknown relevance that constitute about 30% of all mutations detectable in the BRCA1 or BRCA2 genes [ 1, 2].
Similar(53)
A potential disadvantage is the unknown relevance of the molecules excreted in urine to the disease of interest.
Our findings highlight a previously unknown relevance of PIK3R1 genotypes for alcohol use disorders and might help discriminate individuals at risk for alcoholism.
Given this extensive support, an experimental characterization of the protein families with unknown relevance for plant biomass degradation in the PDMs, and their respective gene clusters, is likely to reveal new biochemical functionalities for plant biomass degradation.
Therefore, A10149T can be classified as a variation of unknown pathogenic relevance.
Finally, we used an antibody against T368+ Elk-1, a phosphoform of unknown functional relevance.
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Since I tried Ludwig back in 2017, I have been constantly using it in both editing and translation. Ever since, I suggest it to my translators at ProSciEditing.

Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com