Cohort studies would benefit from comprehensive policies that address various categories of findings, including those with clinical significance, those of unknown significance, those with implications for biological relatives, and incidental findings [ 34].
Our observations are important given the unknown implications of evolving diagnostic and treatment approaches over this period of time.
Taking a broad view of prognostic outcomes may generate new knowledge at the start of translational pathways with (as yet) unknown implications for developing new interventions.
Pandemic (H1N1) 2009 was a novel disease with unknown implications; therefore, implementation of an aggressive surveillance approach was needed to better characterize and understand its public health effects, particularly among school-aged children.
Taking them out of context and then placing them in relation to each other in a book which becomes a context: a coherent linear progression of sequential information which can make something new happen and speak about this idea of the fear of unknown technology and its implications.
Taking them out of context and then placing them in relation to one another in a book that becomes a context: a coherent linear progression of sequential information that can make something new happen and speak about this idea of the fear of unknown technology and its implications.
I suppose I could take study drugs if I wanted to - to compete - but I don't feel I should, perhaps morally or maybe because of the unknown health implications.
We show that diagnosis even late(r) in life, in patients previously labelled as having drug-resistant epilepsy with intellectual disability of unknown cause, can carry important implications for affected patients; rational treatment changes can be instituted, with possible benefit as we and others have shown, even after years of drug resistance.
Although its actual formulation is straightforward, the treatment of unknown classification, a consideration of the implications for censoring, the effect on genomic predictors and diagnostic analysis have not been previously considered.
Although the aetiology of this disease is unknown, the implication of permeable circulating factor(s) in the pathogenesis of primary FSGS has been suggested for a long time for the following reasons.
