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Assuming the population dynamic model gives a reasonable approximation to reality, Λ0 should converge to a <img src="http://journals.plos.org/plosone/article/asset?id=info?doi/10.1371/journal.pone.0012114.e015.PNG" class= inline-graphic"/> distribution, where n = inline-graphicber of unique cells (2 sexes×29 years×10 age classes) and p is the number of estimated model parameters.
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MSCs possess the ability to self-renew and differentiate into several lineages, and are recognized by the expression of unique cell surface markers.
Cross-communication between signaling pathways is crucial for the integration of the multiple intracellular responses elicited by simultaneous signals, allowing the generation of unique cell outputs.
Obtaining a comprehensive understanding of unique cell biology of calvarial osteoblasts from dissimilar embryonic origins, and understanding how those differences translate into variable potential strategies for endogenous bone regeneration, is critical to the optimization of cell-based skeletal tissue repair modalities.
16, 37, 38 Most importantly, such approaches are not limited by the existence of unique cell surface markers to identify a particular cell sub-population of interest.
We recently reported the existence of unique cell-in-cell structures in clinical cancer specimens, in which lymphocytes penetrated both malignant and normal ECs.
Notably, the relative distributions and size of the neurons labeled by KCNAB1 and KCNS1 suggests that some genes may be specific markers of unique cell types in RA.
These differences likely reflect both the targeting of unique cell populations by each PAMP and the specific prostanoid pathways associated with these targets.
Connective tissues such as bone, ligaments, cartilage, and menisci consist of unique cell populations in their matrix that can adapt to changing mechanical environments.
The other acetyl-CoA carboxylase-related proteins involved in the biosynthesis of unique cell wall lipids may be explored as possible targets for new drug targets.
CSCs have been identified in many tumor types and cell lines based on the expression of unique cell surface markers such as CD44, CD24 and CD133 or their ability to efflux lipophilic, fluorescent dyes such as Hoechst 33342 [ 8- 11].
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