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Future studies are needed to clarify the complex networks of unidentified signalling pathways concerned.
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It seems probable that, as with hippocampal LTP, multiple as-yet unidentified signalling pathways will play a role in the induction, expression and maintenance of cerebellar LTP.
Also, SL-1 and SL-A caused upregulation of transcripts involved in phosphatase/kinase activation, PTPRE, PTPRN, PPP1R11, and PPP1R14A, which could influence unidentified signaling pathways in mycobacterial infection (Supplementary Table 1).
Such induction of chemokines by IL-27 in RA-FLS was not completely inhibited by those inhibitors, other unidentified signaling pathways might therefore contribute to the chemokine expression.
These as yet unidentified signaling pathways may also be exploited for neuroprotection.
Finally, our data demonstrate that ERK1/2, but not PI3K and mTOR, contributes to extracellular ATP-induced VVEC rearrangement into tube-like networks in Matrigel, suggesting that additional, as yet unidentified signaling pathways are involved in endothelial tubulogenesis.
For example, mutations in vacuolar protein sorting genes that affect the multivesicular body pathway, such as vps27 ∆, cause mat formation defects independently of Flo11p, presumably by affecting an unidentified signaling pathway.
Thus, it appears that the Klotho activation of p46-JNK and p54-JNK may be mediated via an as yet unidentified signaling pathway that is linked to Klotho expression.
Our data demonstrate that there exists an as yet unidentified signaling pathway that leads to GLUT4 recruitment and glucose uptake and that this pathway is activated by a serum factor.
Thus, autophagy can be induced under nitrogen-starvation by an as-yet-unidentified signaling pathway independent of the Npr2-Npr3 and Gtr1-Gtr2 axis.
It may act redundantly with other D-box binding factors, such as tef2, or with other as yet unidentified light signalling pathways.
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