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Microcirculatory flow abnormalities at the baseline were independently associated with an increased risk of unfavourable outcome.
Furthermore, multivariate regression analysis identified presence of cirrhosis per se as an independent predictor of unfavourable outcome.
As microcirculatory disorders have been identified as strong predictive factors of unfavourable outcome, there is a need to develop accurate parameters at the bedside to evaluate tissue perfusion.
As microcirculatory disorders have been identified as strong predictive factors of unfavourable outcome, there is a need to develop accurate parameters at the bedside to evaluate tissue perfusion [8].
Plasma should not be used to correct abnormal INR or PTT in nonbleeding patients who have no planned surgery or invasive procedures, because there is no correlation between coagulation tests and risk of bleeding [45], but data show that plasma transfusions increase the risk of unfavourable outcome [27, 28].
However, the Eurotherm study [86] showed that TTM had a negative effect on neurological outcome at 6 months with an odds ratio of unfavourable outcome after adjustment at 1.53 (1.02 2.30) (P = 0.04); favourable outcome (Glasgow Outcome Scale Extended score 5 826%6% in the TTM 32 35 group versus 37% for patients in the control group (P = 0.03).
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Early prediction of unfavourable outcomes is difficult but crucial to improve resource allocation.
No association was found between plasma levels of nevirapine and incidence of unfavourable outcomes in this group.
Thus, our finding of unfavourable outcomes in patients with ScvO2 below 60% is in line with previous reports.
Mortality is recorded essentially without error and could be considered as an extreme on a continuum of unfavourable outcomes.
Higher RDW value is a risk factor used for the determination of unfavourable outcomes of chronic heart failure [ 5, 12, 13].
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