Sentence examples for of trial dose from inspiring English sources

For all subjects, regardless of outcome or length of trial, dose was not correlated with CYP2D6 or CYP2C19 metabolizer status (see Table 3).

In the Phase I part of the trial, dose escalation of irinotecan was achieved without any DLT, and the recommended Phase II dose was irinotecan 180 mg m−2 once every 2 weeks with fixed-dose sorafenib 400 mg b.d.

For pharmaceuticals, systemic dose data are generated routinely in nonclinical safety studies very early in the toxicity testing program and play a major role in the selection of clinical trial doses.

However, due to significant heterogeneity in population, body composition measurement, length of trial and dose of LCn-3s some trials have reported no effect [ 45- 50], while others have indicated some effect [ 51- 54].

In the COMACS study children were assigned to dosing strata on the basis of pre-trial dose levels.

Docetaxel was administered within the confines of ongoing trials (dose: 100 mg m−2 within SCOTROC 1 and 100/75/25 mg m−2 within SCOTROC 11).

On may argue that there is no benefit of further dose escalation after resection due to failure of trials involving dose escalation or additional radiosurgery to the tumor bed [ 38].

Notably, in two out of four trials, doses of metformin that are effective in increasing median lifespan in other tested strains were actually detrimental to the viability of eat-2 mutants (Fig. 2A and Table S1D).

A rapid release form of bromocriptine (RR-bromocriptine; Cycloset®) is used in several of these trials, dosed at 4.8 mg per day.

The total trialed dose of 1800 mg/day was preceded by a titration schedule to optimize tolerability.

National Insurance number (NINO) of UK citizens, or passport number and country of origin of non-UK citizens, as a unique identifier, and date of last dose of trial medicine, or that the volunteer was never dosed.