Treatment was allocated using a randomisation list of treatment allocation codes prepared by the contract research organisation responsible for operational management of the study.
The adaptation of treatment allocation in response adaptive designs is formulated as a Markov chain.
It is less certain how much bias is associated with different methods of treatment allocation.
A new target proportion of treatment allocation is proposed under the criterion and related simulation results are presented.
Interviews explored men's recall and understanding of chance, comparison, and equipoise, and reasons for consent/refusal of randomization and acceptance/rejection of treatment allocation.
Strokes and reinfarctions were adjudicated by independent committees who were unaware of treatment allocation.
However, the descriptions of the method of treatment allocation procedures and allocation concealment often remained inadequate.
The order of treatment allocation was randomized.
Assessors were unaware of treatment allocation.
However, participants were unaware of treatment allocation.
b"Was the concealment of treatment allocation adequate?".
