Sentence examples for of trail also from inspiring English sources

The soluble ectodomain of TRAIL also assembles into trimeric molecules but is in contrast to the membrane-bound molecule poorly active despite receptor binding.

Therefore, the high levels of soluble TRAIL documented in the conjunctival sac fluid may suggest an important role of TRAIL also in modulating the inflammatory and angiogenic response in the eye [ 64].

Surprisingly, previous investigators have reported the toxic effects of TRAIL also on normal primary human cells, including hepatocytes (Jo et al, 2000), keratinocytes (Leverkus et al, 2003) and endothelial cells (Li et al, 2003).

To determine whether Bortezomib potentiates the activity of TRAIL also in melanoma cells, we first tested it alone and found that at 4 5 n M it inhibits the growth of all melanoma cell lines.

But the vast network of trails also takes us through and up and over that landscape, then steeply back down.

In past years, some sections of the trail also used metal diamond markers with the AT logo, few of which survive.

The treatment of fibroblasts with TRAIL also enhanced the expression of a number of genes involved in tissue remodeling, including those related to the transforming growth factor (TGF) beta pathway.

This trail also provides views of Trenton, Georgia, neighboring Sand Mountain, and of Cloudland Canyon.

Combination of tubulysin A or pretubulysin with TRAIL also displays markedly augmented effects on the activity of pivotal cell death proteins such as caspase-8, Bid or cleaved PARP as shown in Figure 5d.

- Intracellular stores of TRAIL have also been found in polymorphonuclear neutrophils - that are released after a variety of stimuli.,, At physiological conditions, TRAIL is capable of binding to four distinct transmembrane receptors in humans: the proapoptotic death receptors DR4 and DR5 or the two decoy receptors DcR1 and DcR2.

A lack of audit trails also meant that the disclosures would have gone unnoticed if they had not been reported by one of the recipients, said the ICO.