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In the other case, deleterious mutations were allowed to occur with rates and effects typical of those inferred from mutation accumulation experiments with bacteria (Kibota and Lynch 1996; Trindade et al. 2010) (supplementary fig. S2, Supplementary Material online).

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Further, the local nature of PRICE assembly jobs (limitation of input sequences to those inferred to derive from local genomic regions based on paired-end information) was intended to avoid the chimeric misassemblies that would be expected to arise when applying reduced alignment stringency to a full dataset.

We found that limiting analysis of relative ASE to regions of the genome with no more differentiating sites than the number of mismatches allowed eliminated the systematic bias toward the reference allele and produced measures of ASE similar to those inferred from aligning reads separately to the maternal and paternal genomes.

Even though we increased both the number of samples (from 16 to 90 individuals) and the number of loci (from 20 to 31), estimates of the rate and timing of growth are comparable to those inferred for the Mandenka, and our 95% credible region is not appreciably smaller.

The alleles inferred from direct sequencing of amplification products from individuals from Okinawa were identical to those inferred from cloning.

> -wrap-foot> To further analyze this phenomenon, we examine the difference of the lengths of IBD sharing intervals between those inferred as actual IBD and those inferred as background sharing.

To get more insight in the functional characterisation of the orthologues of non-metazoan lineages and those inferred in LECA, we studied their functional domain organisation in representatives of each eukaryotic phylum (Figure 4).

Thus, it is encouraging to observe that most inferred positions throughout the LRR domain of orthologous GALAs coincide with those inferred in individual LRR repeats analysis on groups of GALA orthologues.

In addition, it was confirmed that the flow paths leaving the region of the potential repository are consistent with those inferred from gradients of measured head and those independently inferred from water-chemistry data.

We compare the patterns of variation in chimpanzees with those inferred from published data on patrilocal human tribes belonging to five different larger cultural/geographic regions, hereafter termed 'tribal groups' (N = 20 tribes, Range = 2 5 tribes per tribal group) [3], [5], [17].

A phylogeny of vertebrate TLR proteins including those inferred from newt transcripts was used to assign newt genes to TLR families.

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