Sentence examples for of this tss from inspiring English sources

On the other hand, the most distal TSS of ctrA (S6 in Figure  1d) almost certainly represents a transcript with a long 5′-UTR (291 nt), because CtrA was shown to bind upstream of this TSS [ 38].

The expression of transcripts originating from this TSS cluster is best described as ubiquitous (Fig. S2).

Because of low expression from the TSS3, further study of the transcripts initiated from this TSS was not pursued in detail.

We then generated luciferase reporter vectors bearing nested fragments spanning the first 0.8 kb upstream of this new TSS [ 45, 46].

Dissimilarities between the studies include the use of 1000 bp upstream and 200 bp downstream of the TSS (this study) versus 1500 bp upstream and 1500 bp downstream by Saxonov et al. We calculated normalised CpG count for the same window, but this did not change the relative distribution of promoters.

The first objective of the gene expression experiments was to determine the location of the TSS for this gene and thereby the distance between the TSS and the motifs.

For this analysis, we chose to estimate transcriptional activity and steady-state RNA by calculating the read density excluding data within 200 bp of the TSS; in this way, we avoided analyzing transcripts that may have prematurely terminated.

VanderKraats et al. observed that gene expression could be negatively regulated by methylation downstream of the TSS (mainly within 3 kb of the TSS), though this methylation pattern was only seen in a small group of genes (37 genes).

Interestingly, both truncated promoters lack the same 491 bp sequence downstream of the TSS suggesting that this region carries sequence information important for mutually exclusive locus recognition.

Interestingly, this study indicated that TCF4 binds just upstream of the TSS of the long OSBPL1A variant as well as upstream of both TRAK1 TSSs.

To date this is the most extensive and accurate map of the TSSs for this bacterium.