Sentence examples for of their functionally from inspiring English sources

Phenotypic differences identified in inter- or intra-species comparisons could be mostly attributed to transcript sequence and expression polymorphisms of their functionally relevant genes.

Our methodology places MS experiments in a larger biological framework, where proteins expressed in a given cellular state may be readily analyzed in the context of their functionally related neighbors.

In line with this, we also found a significant inverse correlation between the expression levels of these ER-regulated miRNAs and mRNA expression levels of their functionally validated target genes - for instance, hsa-miR-221and hsa-miR-222 have been shown to target the CDKN1B and ESR1genes (see Table S20 in Additional file 1).

Since an intragenic mutation of tra1 -R3590I also suppressed F3744A, we propose that Tti2 is required for the folding/stability of the C-terminal FATC and PI3K domains of Tra1 into their functionally active form.

File structure system has several configurations, each of which have their functionally equivalent yet an independent configuration written in different programming logic.

Slevin et al. in this issue of Structure reveal the architecture of a hidden set of polo boxes from the divergent PLK4, a critical player in centrosome duplication, shedding new light on the evolution of PLKs and their functionally related kinase ZYG-1.

The expression profiles of the genes encoding the components of the costamere, filament system and Z-disk of muscle, as well as their functionally related paralogs (see Additional File 1) were plotted in three dimensions to include (1) the expression level of myoblasts, (2) the expression level of myotubes and (3) muscle specificity (see Additional File 2).

Reduced LC frequency in aged mice combined with their functionally defective of priming T cell immunity could contribute to age-related skin diseases.

The union of the set of known biomarkers and their functionally-related genes represented the "network seeds".

Although our divergent iPGM and dPGM query proteins gave clear and consistent results, it is known that identification of PGM orthologs based on sequence similarity alone can be unreliable because of their similarity to functionally more divergent members of the alkaline and acid phosphatase superfamilies to which they belong [11].

Another possibility for creating templates in the absence of experimental data on functional sites is to iteratively exploit evolutionary constraints: first to identify evolutionarily important residues that suggest 3D templates, and then to sort which of their matches are functionally relevant.