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To finish, we discuss the scope of the present conclusions.
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For a full justification of the present conclusion, further detailed investigations involving the robustness of the temporal and spatial pattern should be conducted.
However, for a full justification of the present conclusion, further detailed investigations on such issues as the reason-ability of the proposed parameter sets and the declustering process are needed.
Such work may not only determine the reliability of the present conclusion, but may also give clues on the contribution of neurobiological differences (seen in ADHD and non-ADHD individuals) in response to the reinforcing effects of drugs of abuse.
In the revised manuscript, I have added some spike raster plots to Figure 1 and Figure 3 to clarify the source of each of the presented conclusions.
In general I found the findings of the paper potentially quite interesting, but it turned out to be very difficult to track down the source of each of the presented conclusions.
Assuming all RNAs mapping within 1000 base pairs of an annotated TSS are TSS-associated RNAs and removing these from the analysis does not change any of the presented conclusions (data not shown).
The present conclusion of experts is that "housefly control has escaped insecticidal techniques and once more must be based on general sanitation".
With the increasing availability of high-throughput technologies, mapping of additional fitness landscapes should allow for the testing of the generality of the previous and present conclusions.
Seven of the papers presented conclusions concerning the impact of users' design feedback on the subsequent design process; that is, whether the issues identified during evaluations lead to change in later versions of the system.
We then summarize the experimental results of and present conclusions).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com