Suggestions(1)
Exact(3)
Deployment of the latter test, owing to its higher sensitivity relative to cytology could permit safely extending screening intervals [ 33, 34].
For instance, combining the GRS with CD serology would enable the high sensitivity of the latter test to minimize the chance of true CD cases being overlooked but still leverage the discriminatory power of the GRS.
Although manual muscle testing (MMT) is most commonly used for the grading of motor strength, we substituted two functional tests of strength in lieu of MMT: the heel-raise test for detection of S1 involvement, and the sit-to-stand test for detection of L3 involvement; the performance characteristics of the latter test have been reported elsewhere.
Similar(57)
With respect to the latter, test results of a maximum symptom-limited exercise test may be required (for example, for persons with heart failure) to establish an appropriate training intensity.
As for the analysis of the latter tests, we develop an elasto-brittle model considering crack propagation, at the Rayleigh wave speed, in loading direction.
When CD4+ T cell-matched asymptomatic HIV+TB− HR subjects from India and HIV+TB− LR subjects from the US were compared, ∼45% of the former and <5% of the latter tested biomarker positive.
In case of a positive result with at least one of the latter tests, the child will be considered HIV-1 infected at day 7 and therefore excluded from the trial.
We admit as a limitation, that neither euglobulin clot lysis time nor thromboelastography/thromboelastometry (TEG/ROTEM) were performed, although some studies predicate a limited role of the latter tests for detecting fibrinolysis [ 38, 39].
Notably, regardless of yeast supplementation, 11 of 12 cows in the latter test exhibited similar trends of pH maintenance (6.5 < pH < 6.8) or gradual decrease during the dry period, whereas average daily reticular pH decreased dramatically after calving.
The pathways mediating responses to von Frey and Randall-Sellito stimuli may be quite distinct; the stimulus required to reach the designated threshold behavior is 1 2 orders of magnitude greater in the latter test.
In the final version of the manuscript we only kept the latter test considering the losable COGs (Additional file 6).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com