Sentence examples for of the fixation process from inspiring English sources
In this work, we employed Partial Wave Spectroscopic (PWS) Microscopy, a nanoscale sensitive and label-free live cell spectroscopic-imaging technique, to analyze the effects of the fixation process through three commonly used fixation protocols for cells in vitro.
While chemical modification and crosslinking by formaldehyde is a direct consequence of the fixation process, fragmentation of RNA can result from a number of different sources: In the time period between sample acquisition and effective fixation, cellular processes and tissue autolysis can result in degradation of RNA, as well as other cellular components [7].
Further studies are warranted to elucidate any significant alteration of MR characteristics as a result of the fixation process.
To assess the effects of the fixation process on RNA quality, comparisons between fresh and fixed tissues, and fixed/sorted cells were performed.
We estimated parameters of the fixation process from the frequency trajectory of rifampicin resistance, assuming that the resistance has a single origin (Additional files 1 and 3: Table S2).
It is important to note that the cup-shape appearance of exosomes visualized by electron microscopy may be an artifact of the fixation process, and their true shape mirrors that of round microvesicles [ 17].
Positive selection is expected to act either on the fixation process of the duplication itself or at new mutations occurring after fixation of the copy in the species (or at both levels successively).
IHC carries many challenges, most notably a variable pattern of staining and the presence of artifacts related to the fixation process.
The aim of this article is to derive explicit analytic expressions for the fixation process of genes whose fitness is modulated by phenotypic mutations, and to show that adaptive phenotypic mutations can undergo positive selection under biologically plausible conditions.
The quality of the RNA extracted from formalin fixed tissues varies and depends on a variety of factors, including the fixation process used, age of the samples, and storage conditions.
Fragmentation of DNA is caused by a number of factors during the fixation process, e.g. low pH formalin over time increases the rate of apurinic/apyrimidinic site formation and eventually decomposition and fragmentation [ 7].
