Sentence examples for of the basic loop from inspiring English sources

Constraints of the basic loop breaking optimization model are displayed in detail.

A mutated catalytic domain (DAPKdel) missing a portion of the basic loop sequence was made by excising the amino acid sequence SRRGVS between S52 and S57 (see Figure S2).

Removal of the basic loop attenuates the dimer to monomer equilibrium, but allows retention of the apparent coupling between the ATP/ADP binding site and the probe binding site.

The use of this combined biophysical and chemical biology approach facilitated the elucidation of a monomer-dimer equilibrium in which the basic loop plays a key role, as well as an apparent allosteric conformational change reported by the fluorescent probe that is independent of the basic loop structure.

These data confirm the role of the basic loop in baculovirus entry into insect and mammalian cells.

The basic loop region of ZIPK is considered key to functional heterodimer formation between ZIPK and DAPK catalytic domains [9].

In bilaterian animals, the core molecular components include Timeless-Timeout, photoreceptive cryptochromes, and several members of the basic-loop-helix-Per-ARNT-Sim (bHLH-PAS) family.

It is a member of the basic-loop-helix-PER-ARNT-SIM (PAS) family of proteins and functions as a ligand-activated transcription factor [15], [27].

On this basis, further modification of the gp64 basic loop was investigated to assess its role in mammalian cell entry.

Mice with a targeted deletion of the basic helix-loop-helix transcription factor, Nescient Helix-Loop-Helix 2 (Nhlh2), display adult-onset obesity with significant increases in their fat depots, abnormal responses to cold exposure, and reduced spontaneous physical activity levels.

The ionic strength dependent monomer to dimer equilibrium of DAPK wt prompted us to investigate the role of a basic loop most likely involved in the dimer interface.