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Miyoshi Y, Nagase H, Ando H et al. Somatic mutations of the APC gene in colorectal tumors: mutation cluster region in the APC gene.
Of the APC mutated adenomas 83% (33/40) showed WIF-1 methylation and of the APC wild type adenomas 61% (25/41) showed WIF-1 methylation (p = 0.048).
The increased concentration of protein markers of the APC correlated with CFH haplotypes in patients and controls, suggesting a genetically controlled activation of the APC.
The arrival of the APC lookbook always causes a flurry of excitement on the fashion desk.
He, T. C. et al. Identification of c-MYC as a target of the APC pathway.
Su, L. K. et al. Multiple intestinal neoplasia caused by a mutation in the murine homolog of the APC gene.
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Mimori-Kiyosue, Y., Shiina, N. & Tsukita, S. The dynamic behavior of the APC-binding protein EB1 on the distal ends of microtubules.
Fas ligand, or antibody to Fas, abrogated the T cell response, by inducing apoptosis of the APC-stimulated T cells.
Mutational analysis of the APC/beta-catenin/Tcf pathway in colorectal cancer.
Thus, the degradation of Venus-ANAPC4 by the mAID-nanobody efficiently abrogated the main function of the APC/C.
John Cryan and Gerard Clarke of the APC Microbiome Institute are particularly interested in how gut bacteria might influence the brain structures involved in anxiety-like behaviours.
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