Sentence examples for of test article from inspiring English sources

There is an approximate 2-week rest period followed by a Challenge phase of a single 24-h patch application of test article applied to a naïve site on the back.

Dose formulations were prepared by dissolving the appropriate amount of test article in the vehicle to achieve target concentrations using a sterile stir bar and sonication.

Dosimetry, in the context of inhalation toxicity testing, is the accurate determination of test article dose (whether that be whole smoke or any other inhalable aerosol) reaching the target cells, and is one of the key components in the establishment of a reliable dose response [19].

Primary Irritation Index (P.I.I). of test article was calculated following test completion.

RNA recovery was determined using a set of blood samples spiked with a known amount of test article (MRX34) in a serial dilution (spike-in samples).

In the chronic bioassay, groups of 50 C3H/HeJ mice received twice weekly applications of 50 microl of test article for at least 2 years.

The purpose of the analyses is to understand the response of test articles to high-enthalpy flows in ground tests and to predict component performance in particular flight environments.

Clinical pathology, traditionally comprising clinical chemistry, coagulation, hematology, and urinalysis evaluations, is established as an integral part of the preclinical safety assessment of test articles (new chemical entities, exploratory novel medicines, xenobiotics), especially in short- and medium-term toxicity studies.

Key effects such as body weight reductions and organ weight changes occurred in rats and mice predominantly at the highest doses of test articles and positive control in the absence of treatment-related gross or histopathological changes.

As reported in several recent reviews, the rate of irrelevant positives (i.e. low specificity) for some studies using in vitro methods (when compared to this "gold standard") means that an increased number of test articles are subjected to additional in vivo genotoxicity testing, in many cases before, e.g. the efficacy (in the case of pharmaceuticals) of the compound has been evaluated.

This approach will become even more important when comparing reported data from an ever varied source of test articles, biological endpoints and exposure systems: dosimetry techniques will be able to unite data and systems with diverse modes of dilution.