Sentence examples for of target lymphocytes from inspiring English sources

Because transformed phenotype of target lymphocytes for BLV is CD5+-B cells [ 39], it is easy to imagine that the proviral load in peripheral blood increases with disease progression.

The effects of chemokines are associated with their level of expression (Anderson, 2008; Sung et al., 2012) and the expression of their receptors on target lymphocytes and macrophages (Allen et al., 2007).

Interestingly, target lymphocytes of CD4+ cells infected with HTLV-1 also polarized their cytoskeleton towards the infected cell.

This complex pathophysiological process is characterized by the infiltration of target organs, with lymphocytes organizing themselves into distinct T- and B-cell rich zones.

This effect was demonstrated to result from abortive infection of target CD4+ T lymphocytes in which infection up to the level of an initiated RT was sensed and a proinflammatory response generated, ultimately leading to death of the infected resting CD4+ T cells.

HIV targets lymphocytes via binding of gp120 to cell receptors and gp120 moves away from or dissociates from gp41.

Together, this implies that the activation state of target CD4+ T-lymphocytes not only dictates the success rate of HIV-1 infection of previously uninfected target cells, but also determines how efficiently integrated proviral genes are transcribed, and thus new virus particles are synthesized in latently infected resting cells upon encounter with T-cell stimuli.

The apoptosis-inducing serine protease granzyme B (GrB) is an important factor contributing to lysis of target cells by cytotoxic lymphocytes.

These approaches enabled visualization of molecules otherwise refractory to genetic engineering (glycans and lipids), enhancement of antibody functions, or targeted lymphocyte engagement for therapeutic purposes.

Thus, companion biomarkers evaluating the potential association between pre-existing immune response at diagnosis and treatment response should arguably also be included in the setting of lymphoma clinical trials where agents targeting lymphocyte signalling pathways are being evaluated.

Controls included the incubation of target cells alone or with either lymphocytes or mAb separately.