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This is of relevance as it will help to understand the importance of systemic components compared to intrinsic muscle factors, such as disuse, in sepsis-induced muscle atrophy.
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But Wheeler, from a similarly Heideggerian position, claims that the way to address the "inter-context" frame problem, as he calls it, is with a dynamical system in which "the causal contribution of each systemic component partially determines, and is partially determined by, the causal contributions of large numbers of other systemic components" (Wheeler 2008, 341).
Few other studies have addressed the complexity of the microbiological and systemic components of COPD or employed real-time electronic tracking of symptoms to identify AECOPD and potential aetiological triggers.
Many organs contain components involved in the synthesis and actions of the RAS, which are largely independent of the RAS systemic components and not accessible to routine laboratory testing [14, 15].
The current studies were conducted to increase understanding of the relative contributions of these proinflammatory and pro-erosive cytokines to the local and systemic components of inflammation and bone loss.
Systemic components of regulation include parathyroid hormone, 1,25-dihydroxyvitamin D3, and calcitonin: local regulators include numerous cytokines and growth factors.
It can be speculated that the cellular model, methodology, or even the bioinformatic input are not yet appropriate to elucidate complex systemic components of cell biology.
The duration of the systemic component can probably be limited to the first four days, similar to the regimen used in the most recent trial and in trials in the intensive care unit.
Because it affects a limited number of joints and has no known systemic components, OA is well suited to local gene therapy [ 78].
We conclude that IFN-γ functions as an acute-phase cytokine in both models of liver regeneration and may constitute a systemic component of liver regeneration.
This scale may also be useful in studies or clinical trials evaluating the systemic component of UC.
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