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The variation in the initiator efficiency is due to lack of sufficient concentration of Cu II).
This is mainly due to the presence of sufficient concentration of catalytic ferrous ions in the reaction system.
In the presence of sufficient concentration of clusters, there is an initial burst of nucleation of small nanospheres.
The use of sacrificial initiator results in the generation of sufficient concentration of the persistent radical, which enables better control of the surface-initiated ATRP.
As expected, mediation with proper surfactant of sufficient concentration (such as PVP) can also lead to a successful coating of silica on the functional core with hydrophobic surface; further work is underway.
In order to test whether the muscimol infusions in Phase 1 or 3 had been in appropriate locations and of sufficient concentration fully to inactivate the critical eyeblink control regions during the consolidation time-window, in Phase 5 their efficacy in blocking the performance of established CRs was tested.
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Successful chemotherapy of cancer depends on the delivery of sufficient concentrations of an effective drug to tumor cells without causing intolerable toxicity to the patient.
We note that, due to the lack of sufficient concentrations of particles above 5 μm in our experiments, we are unable to make conclusions within this size range.
For example, although curcumin, a phytochemical present in herbs and spices, possesses various biological activities and inhibits the growth of various cancer cells in vitro, its low systemic bioavailability following oral dosing has been suggested to limit access of sufficient concentrations for pharmacological effect in certain tissues [ 26].
Four factors are thought to be required for the development of the mTSS: (1) vaginal colonization with a toxigenic strain of S. aureus; (2) production of TSST-1; (3) penetration of a sufficient concentration of TSST-1 across the epithelium to cause the disease; and (4) absence or insufficient titers of neutralizing antibody to the toxin.
Although the use of sacrificial initiator would alleviate this problem, by way of generating sufficient concentration of Cu II) to control the atom transfer equilibrium, this would result in the formation of free polymer that will have to be separated from the reaction mixture.
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