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Experimental results prove the effectiveness of such a selection, since target architectures outperform the conventional 2-D FPGAs.
The success of such a selection experiment proves that there was genotypic variation for ocellus number and arrangement in the original population of normal flies, but that all the different genotypes mapped onto the same phenotype.
Changes in the mutation-selection balance for sex-limited genes are part of such a selection protocol, but, given the small proportion of sex-limited loci in the D. melanogaster genome [58] and the low rate of mutation accumulation expected in fairly large populations such as these [59], they are unlikely to explain a major fraction of the fitness changes observed in the ML lines.
However, little is known about the perspectives of such a selection strategy in beef cattle.
Ultimately the effect of such a selection bias on our results is probably limited.
To keep robustness of such a selection the bootstrap method (drawing with replacement) was used to generate a training set.
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In addition, high EHH around the putative advantageous variants may also be observed, though the power of this test for such a selection scenario has not been investigated.
The paper at hand performs a much more comprehensive analysis of such a relay selection protocol than previous work in this area.
Kovach et al. (2012) demonstrated the potential long-term consequences of such a strong selection event quite eloquently.
Despite application of such a «negative selection» biomarker, the KRAS-wild typatientent population benefits from anti-EGFR strategies in less than half of cases.
Even though this may seem contradictory, since it suggests evolutionary innovation by degeneration, there are several examples of such a positive selection for gene loss [ 50– 50].
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com