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Exact(32)
Hence, the extraction of new structural information is accompanied by a decrease in the number of isomers that meet constraints imposed by the experimental data (spectra), and the process of structure elucidation reduces to the successive imposition of structural constraints on the number of possible isomers up to the extraction of complete structural information.
However, our data do not rule out the possibility that the putative relief of structural constraints was due to the introduction of alanine at the structurally restrictive position.
The fulfillment of structural constraints is ensured by the generation algorithm, which exhaustively yields all structures that meet the constraints.
Perhaps because of the absence of structural constraints, however, disordered proteins typically show higher rates of mutations than do structured proteins [ 88], so it is often more difficult to identify sequence relationships among disordered proteins.
Marshall aid was premised on the identification of structural constraints, on national targets for the main economic variables and on a sequenced approach to meeting objectives.
After publishing a few issues, the magazine closed because of structural constraints, like the unofficial blocks on cultural transactions across borders and tensions inside the editorial team.
Similar(28)
In our quantitative models, we clarify the notion of structural constraint by quantifying how large must be a disadvantage for altering structure in order to outweigh the large benefit of escaping host immunity.
The argument is fourfold: since structure and agency are understood as inseparable, (i) the causal influence of material properties are undervalued, and (ii) different degrees of structural constraint and freedom of actors are ignored.
Compared to the GA method (summarized in Figure 1, panel B) we don't use node degree to define the vertical axis, but instead a local measure of brokerage base on paths of length two, similar to the notion of structural constraint [8]: C i = ∑ j ( a i j + ∑ k a i k a k j ) 2. (4).
Another structural feature, the addition of extra sequences, is plausible if we assume the reduction of structural constraint as a consequence of specialization in the inter-ZF interaction.
The hypothesis of structural constraint implies that, if an escape variant arose, its fitness would be so greatly reduced that it could not spread.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com