It was developed with the idea of balancing the average probability of a single occurrence of a domain pair against the actual frequency of occurrence over interacting and non-interacting protein datasets.
For example, the costs associated with secondary dressings are estimated at £13.16 for complete onward management of a single occurrence of "wound enlargement".
Bioinformatics analysis revealed a ∼30-bp∼30-bpdromic consequenceequence motif shared by all of the repeat occurrences and most of the single occurrence sites, verifying that ϕC31-mediated integration into pseudo attP sites is significantly guided by DNA sequence recognition.
However, the causality of a single occurrence in an early phase clinical trial is difficult to assess, and vasculitis has also been previously reported with licensed hepatitis B vaccines [22].
Regarding light chains, the use of two different IGKV genes (1 and 3) was observed: IGKV1-39*01 and IGKV1 -16*01 (5 occurrences each), IGKV1-17*01 (4 occurrences), IGKV1-27*01, IGKV1-13*02 and IGKV1-9*01 IGKV1-9*01nces each) and finally one occurrence of IGKV1D-13*01, plus three single occurrence of IGKV3 (IGKV3-7*02, IGKV3-11*01 and IGKV3-20*01).
On the other hand, one quarter of all sheep alleles sampled had expansions or contractions in this region: 43 occurrences (20%) of "+6nt" variants, 4 occurrences of "–12nt" variants, and a single occurrence of a "+9nt" variant (Table 4).
We construct a dataset comprising 10 sequences of 200 nt in length, each sequence containing a single occurrence of a perfectly conserved motif of width 8 bp.
From 238 isolates, we only found a single occurrence of a loss of function mutation in lasI gene and intact lasR gene.
For any pair of nucleosomes that are d bps apart, such that d < 100, we count a single occurrence of a (putative) linker of length d.
Of these, 359 were represented by more than a single occurrence of the peptide in the dataset.
