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Similar compounds from chemogenomics data presents a list of similar compounds (Tanimoto similarity values given) from CTD, ChEMBL data that include the relationships with compounds and genes/diseases.
Similar compounds from Systems data presents a list of similar compounds (Tanimoto similarity values given) from KEGG data that include the relationships with compounds and Pathways/Enzymes.
Right-clicking on it and choosing View: MarvinView shows the output table of similar compounds, their similarities to the input compound and their associated targets.
Activities of similar compounds presents a list of similar compounds (Tanimoto similarity values given) in PubChem that have been tested in bioassays, and shown to be either active.
Among others, chemogenomic approaches have enabled: (i) the prediction of protein targets for new compounds based on the bioactivity profiles of similar compounds, [7 9] (ii) the study of protein similarity on the basis of the similarity of their ligands, [10, 11] and (iii) receptor deorphanization [12].
For all libraries, pharmacophore-based similarity with the omission of two features yielded the largest number of similar compounds yet, these numbers drastically decreased when requiring complete matching, probably due to the large number of feature in this pharmacophore model (seven features).
It and a gaggle of similar compounds formed a dusty, trash-strewn pit stop strategically located on the jeep track leading to the Tora Bora foothills.
A number of similar compounds having vitamin E activity and classified as tocopherols or tocotrienols have been isolated.
"The UK is leading the way by using generic definitions to ban groups of similar compounds to ensure we keep pace within the fast moving marketplace for these drugs," said Iversen.
The principle of countercurrent distribution is similar to that of chromatography; both procedures are used for analysis and purification of mixtures of similar compounds.
Similar(1)
Optical diffuse reflectance spectra of these compounds suggest that they have notably lower band gaps than those of the similar compounds composed of aliphatic alkyl amines.
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