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That relationship seems to have already been shattered, with the Russian President's warning of "significant consequences for Russian-Turkish relations" coming hours before a slew of moves telling Russians to stop visiting Turkey and news stories in state-sponsored outlets accusing Ankara of "dealing with radical Islamists".
The new extension of design deeper into organizational culture offers the possibility of significant consequences.
It predicts this level annually in the five years after controls on worker movements end, warning of "significant consequences" for housing and jobs.
It is the view of this panel and the activist organizations that comprise the Darfur movement that the way forward should involve deeper diplomatic engagement that is rooted in multilateral pressures and the credible threat of significant consequences for policies or actions by Sudanese parties that undermine peace efforts and lead to worsening humanitarian conditions.
The C4 shuttle operating in maize possesses a number of significant consequences for its primary metabolism and tolerance to stress.
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But from a rugby point of view, and from the point of view of the competition, this is an issue of significant consequence.
So there is really nothing of significant consequence to this courtroom skirmish, though it does highlight the potential that a significant minority of Elan's shares could still remain outstanding after Royalty Pharma's acquisition.
"We are doing all of this not to address run-of-the mill cyberintrusions, but to stop attacks of significant consequence — those that threaten life, limb and the country's core economic functioning," General Dempsey said.
One of the possible successors to David Cameron as Prime Minister, Mr Johnson's views on corporation tax could be of significant consequence were he to come to lead his party.
The Treasury Department said its analysis revealed "a basic math error of significant consequence," while S.& P. argued that it was not an error but simply a change in assumption that did not affect its final decision to cut the rating.
This observation is of significant consequence to the design of the composite fabrication process.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com