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Comparison between the five sources of data showed a remarkable consistency of CNA across the genome, indicating a high degree of non-randomness to the CNA and equally importantly, an absence of significant array batch effects (Figure S1).
Three supplemental images are included as Additional file 3 (BRIG plot of genomes compared to PAO1), 6 (BRIG plot of genomes compared to PAHM4), and 7 (heat map of significant array results).
A.twe: A. tweddlei; M.est: M. estherae; P.sim: P. similis; R.chi: R. "chilingali"; "ns": not significant; superscript numbers: when multiple array features represent a gene, these numbers indicate the number of significant array features and the total number of array features for that gene represented in the table by a single GenBank number and data row.
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The matrix A k in Equation (2) was approximated by zeroing elements less than a threshold λ (let B k = [ A k ]>λ be this matrix), and the dimension of B k T corresponds to the number of significant arrays contributing to the k SVs in A k.
The downstream signalling cascade of RIPK1 may provide a significant array of novel candidate of therapeutic targets.
Of the 256 genes, 53% (135) showed a significant association with smoking status in an age- and sex-adjusted logistic regression model; 74% (59) of the 80 significant array genes remained significant by qRT-PCR (Additional file 1: Table S5).
He pumped his biceps, clenched a fist in front of his chest, and exposed a significant array of age-appropriate dental work.
This first set of results indicates that these parasites possess a significant array of CK2 enzymes expressed in different cell compartments and that they differ in their ability to respond to extracellular protein targets.
A multivariate approach to design a statistically significant array of experiments was employed to evaluate and estimate optimization of PC-immobilization process factors.
The significant array of liver support systems available would suggest that the design, clinical utilization and end points for success remain poorly defined.
It is crammed, but nicely so, with portrait after portrait by a significant array of self-trained, outsider artists.
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