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In parallel, development of signalling systems requires a lot of attention.
In particular, the authors have begun to interpret system behaviours and their underlying molecular mechanisms through the lens of information transmission, a principal function of signalling systems.
The implications of such a shift in selective pressure to the evolution of signalling systems of different modalities, however, remain largely unexplored.
Considering the ecology and evolution of signalling systems, it is reasonable to predict that the egg recognition pheromone may have another practical function, like cuticular waxes which provide egg recognition cues and protect eggs against desiccation in some ants [13], [14].
Interestingly, during endochondral ossification, several other groups of signalling systems have been found to interact with IHH [ 29].
Boolean models were invented for modelling of gene regulatory networks [ 1], and are now used in a variety of signalling systems [ 2- 4].
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The proposed model reflects the constraints of signalling system and train protection operations rules.
This nonclassical mode of signalling system cross-talk, in distinction to receptor activation induced by cognate ligands, has been termed 'signal transactivation'.
G.P.N. consults occasionally with multiple pharmaceutical and biotechnology companies about flow cytometry based analysis of signaling systems.
A third innovation is generalizing principles of quantitative information theory to apply to a broad range of signaling systems.
Analysis of the system design principles of signaling systems requires model systems where all components and regulatory interactions are known.
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of signals systems
of signalling elements
of signalling proteins
of operating systems
of signalling pathways
of signalling cascades
of signalling failures
of signalling latencies
of failing systems
of signalling sites
of signalling molecules
of signalling technologies
of signalling messages
of signalling problems
of communicating systems
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