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*Year of second kidney transplant.
The prognosis of second kidney transplant recipients (STR) compared to first kidney transplant recipients (FTR) has been frequently studied.
Whereas the prognosis of second kidney transplant recipients (STR) compared to the first ones has been frequently analyzed, no study has addressed the issue of comparing the risk factor effects on graft failure between both groups.
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The regimen taken between 1988 (year of first kidney transplant) and 1993 was not recorded.
A low tubular MT score was therefore associated with impaired renal function at the time of first kidney biopsy and with an increased risk of a poor renal outcome in the present SLE cohort, indicating that renal MTs exert important renoprotective functions in the lumen of proximal tubules during lupus nephritis.
We propose that kidneys from DCD donors should be allocated through a mechanism to maximize the possibility of simultaneous transplantation to ensure prolongation of the CIT of the second kidney does not occur.
What about organ donation that goes beyond what is currently permitted, such as the donation of the second kidney or donation of an organ necessary for life?
Melanoma patients with a parental history of kidney cancer were at very high risk of developing second kidney cancers (SIR 13.1, three cases).
Unfortunately of great concern was the finding that paradoxically this had an even greater adverse effect on the CIT of the second kidney.
One potential mechanism to minimize the CIT of the second kidney from a DCD donor would be the allocation to 2 separate institutions.
In such patients, the anatomical and functional status of the second kidney needs to be confirmed by USS, intravenous urography and nuclear scintigraphy.
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