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This protein possesses a RsmD-like rRNA methyltransferase domain (IPR004398) and HHpred searches detect similarity to a number of methyltransferase families with roughly equal probability, including type I restriction-like DNA methyltransferases (e.g., 2okc_A, 2ar0_A, both 99.8% probability) and rRNA methyltransferases (e.g., 1uwv_A, 99.7% probability, 3g89_A, 99.6% probability).
[Mutation sampling in such experiments is nearly unbiased because genetic drift overwhelms natural selection during the extreme bottlenecks; without selection, all non-lethal mutations can fix with roughly equal probability, regardless of their deleterious, advantageous or neutral effects [ 22- 24].
One way to conceive of "roughly equal" is as a "roughed up" version of "equally good".
The patients were of roughly the same age, and their cancers were of roughly equal severity.
Separate your food and other items into two bags of roughly equal weight.
Both sweeteners are made up of roughly equal amounts of glucose and fructose, they say.
That form entails at least three, but usually four, acts of roughly equal length.
Moreover, in a list-based task, items are independent and of roughly equal importance.
Of roughly equal authority as the steward was the marshal.
The liposome suspension was sonicated briefly to obtain liposomes of roughly equal size.
Consultants were then divided into three volume bands of roughly equal operation numbers (table 1).
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com