A complete quantification of biologically relevant memory would involve first perturbing the cell with all possible sequences of complex environmental inputs it might experience in the wild in each of its growth modes, then measuring all cellular responses to these perturbations, and, finally, quantifying the degree and distribution of history-dependence in these responses.
"A patient suffering from intrusive traumatic memories would take a pill containing a drug that would enter the brain and activate Npy1 receptors and then be exposed to a virtual experience of the trauma," says Gross, "and we predict that the combination of receptor activation and trauma exposure and recall would promote the selective erasure of the relevant memory".
We use the term "flashback" throughout this paper in an experimental psychopathology context, that is, as an experimental analogue of a broader clinically relevant memory phenomenon.
Furthermore, understanding the potential mechanisms involved in long-term courtship suppression would greatly increase our understanding of in vivo ethologically relevant memory formation.
Another commonly tested type of AD-relevant memory is that of recognition memory.
Overall, by determining the fate of motivationally-relevant memory traces, post-learning sleep, even in the form of a nap, sharpens the skyline of our memories.
Whereas formation and expression of sweet-taste-reinforced STM is insensitive to satiety state, artificial formation and expression of nutrient-relevant memory require flies to be hungry.
However, these models have not yet suggested mechanisms for selective preservation of particularly important or relevant memories.
These findings demonstrate that post-learning sleep determines the neural fate of motivationally-relevant memories and promotes a value-based stratification of long-term memory stores.
Following from previous research in which post-encoding suggestions of threat led to the development of a memory bias (in the presumed absence of an attentional bias; Senn & Radomsky, 2012), we sought to examine whether the development of a similar threat-relevant memory bias could be fostered via a purely informational pathway.
