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However, these initial genotyping technologies were of relatively low throughput and required significant effort per data point.
However, casting and running the gels render these protocols time consuming; hence the protocols are of relatively low throughput.
Another factor for proteomics is that it is of relatively low throughput compared to other omics technologies in all three phases of discovery, verification and validation and, therefore, fewer biomarkers have been discovered and validated in proteomics.
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This bottleneck is evident in the first series of relatively low-throughput and labor-intensive C. elegans drug screens [28], [29], [33], [55], [56].
Those better strains were not identified with the screening because of the relatively low throughput of the systems used with only 27 candidate strains in the incubator screening and 81 strains in the robot screening.
Until recently, the majority of such maps was based on relatively low-throughput marker technologies, which limited marker density across the genome.
A modification of a standard method of fluorescence in situ hybridisation (FISH) is described, by which a combination of several substrates and probes on single microscope slides enables more accurate comparisons of the distribution and abundance of chromosomal sequences and improves the relatively low throughput of standard FISH methods.
The generally low sensitivity of standard in vivo toxicity tests to immunotoxicities, inter-species variability in the structure and function of the immune system, high costs and relatively low throughput of in vivo tests, and ethical concerns about animal use underscore the need for trustworthy in vitro assays.
Combined with the relatively low throughput rate of patient examination of high-field MRI (≥1.5 T), HCA technology in its present state is likely to carry a high molecular imaging examination cost similar to that of PET imaging.
Microbiologists are nowadays limited mostly by the relatively low throughput of molecular experiments that remain necessary to test the functionality and biological role of proteins newly identified using in silico approaches.
However, most available assays allow only a relatively low throughput of samples.
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