Sentence examples for of random signatures from inspiring English sources

We counted the number of random signatures that had smaller P values than the P value of their corresponding top 37 signature and divided it by 1,000.

A method to test a predefined number of random signatures of a predefined size on all the data sets was developed.

Subsequently, random permutations were performed in which the D values were randomly assigned to each miRNA within each signature, so that an index of the number of the miRNAs associated with the number of random signatures (E 0, E 1, E 2...E S) was generated.

The CDMA system used here relies on the use of random signature sequences of length 31.

Nevertheless, a good set of signature vectors can be found by generating a large set of random signature vectors and picking the one that maximizes the expression in (20).

Statistical significance of the classification was evaluated by comparing the overall accuracy of the 12-gene signature with that of 1000 random signatures of the same size using the same algorithm.

We found that 4.6% of the random signatures were significant (P < 0.05), of which 2% had HR > 1 (Fig 3D).

To control false positive results from the log-rank tests using top 37 signatures and the 31 test datasets, we compared the predictive ability of each of the top 37 signatures to 1,000 random signatures of identical length (ranging from 12 to 1,019 genes).

The 34 other prognostic signatures were unable to discriminate prognosis groups in the majority of test datasets when compared with random signatures of equal length (median P values > 0.05).

Thus, an adjusted P value is determined dynamically by adjusting the P value from one of the top 37 signatures using the P values from 1,000 random signatures of equal length in the same test dataset.

To assess whether the association between our signature and metastasis-free survival was specific in the NKI295 cohort, we generated 1,000 random signatures of equal size to the HIS (that is, lists of randomly picked 76 genes) and tested their association with outcome by using the same method as detailed earlier.