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However, these observations need to be interpreted with caution since many bacterial antibody assays using whole-bacterium lysates are of questionable specificity, and the same applies to polymerase chain reaction-based detection and DNA-DNA hybridization using a complex nucleic acid mixture containing an excess of human DNA.
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The complex interactions that exist between different signalling pathways makes interpretation of these data complicated and this is made worse by the questionable specificity of some of the pharmacological interventions.
Interpretation of those experiments was limited by the questionable specificity of these agents and their toxicity at the concentrations needed to observe any protective effect.
Based on the lower frequency, as compared to anti-Ro and anti-La, and the questionable specificity, we conclude that testing for anti-α-fodrin antibodies does not have much additional value for the diagnosis of Sjögren's syndrome.
The Flyers lost because of questionable goaltending.
The first method is of questionable value.
However, your articles were of questionable taste.
A lifetime of questionable decisions follows.
Of questionable character; dubious; disreputable.
Steer clear of questionable sites.
Documents of questionable veracity are okay.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com