Sentence examples for of proven efficacious from inspiring English sources

The underuse of proven efficacious therapies in patients with diabetes is a common theme in health services research and does result in adverse patient outcomes (20).

Given the lack of proven efficacious treatments for Balamuthia encephalitis, it is unclear whether even earlier diagnosis at HD 1 would have impacted the fulminant course of our case patient's infection.

This level of concern by the World Health Organization and other health-care authorities and providers is based on the high lethality of EBOV-Zaire in humans (up to 90%), its high communicability though body fluids, the high incidence of infection in primary health-care workers and the total lack of proven efficacious drugs or vaccines.

The potential clinical impacts of missing this information are unknown, but would include drug interactions, adverse effects or other side-effects otherwise attributed to proven efficacious medications.

Among conditions initially placed in the core panel category on the basis of the survey score, CPT-II washifteded to the secondary target category on the basis of the lack of a proven efficacious treatment.

The proteasome inhibitor bortezomib, which eliminates PCs and is approved for the treatment of multiple myeloma, has proven efficacious in an experimental model of SLE clinically and by significantly decreasing autoantibody titers in preventive and therapeutic approaches [ 205].

Many of these strategies have proven efficacious in the short term, but less successful in long-term weight loss and maintenance of that weight loss.

Drugs targeting aberrant HIF activation have been introduced into the clinic and have indeed proven efficacious, most of all in the treatment of metastatic ccRCC.

Administration of bovine colostrum has already proven efficacious in treating bacterial and viral enteritis in babies and infants [ 13].

Applications of acceptance-based interventions have proven efficacious in fostering health behaviors, such as weight management [ 19, 20], physical activity practice [ 21], and smoking cessation [ 22].

Although a few of them have shown limited efficiency in animal models or in small clinical studies, none of the currently available antioxidants have proven efficacious in a large-scale controlled study.