A major limitation of GMR models concerns automatic selection of the proper number of model states, i.e., the number of model component densities.
Also noticed in[5] was that the increased number of adaptation parameters did not guarantee a good performance when the amount of adaptation data was small (the determination of the proper number of adaptation parameters for given adaptation data is a model-order selection problem).
This process needs to be accurately regulated and coordinated to ensure the generation of the proper number of terminally differentiated cells for each of the many neuronal cell types that compose the mature CNS (Iijima & Yokoyama, 2007; Valenciano et al, 2009; Vecino et al, 2004).
The formation of the proper number of tip-cells is regulated by delta-like ligand 4/(dll4)/Notch receptor signaling, which forms a lateral inhibitory circuitry, whereby VEGF triggers expression of dll4, which in turn inhibits the VEGF responsiveness, and hence the induction of the tip-cell phenotype in neighboring endothelial cells [2], [3], [4], [5], [6].
In most vertebrate organs in which symmetric divisions are the rule among stem cells, homeostasis consists in the life-long maintenance of the proper number of differentiated cells, replacing lost cells by new ones.
Interestingly, it is found that the nanovector can be fully taken up with proper number of DNA molecules on its surface.
We also demonstrated that variation of the RSS between the actual and reduced data provides a means of estimating the proper number of elements.
In our case, the 'mission' of maintaining the proper number of developed spinal cord neurons was achieved by the toxicity resulting from early and prolonged exposure to ginkgotoxin.
Aloha-based algorithms estimate the number of tags and assign the proper number of slots to reduce the probability of tag collisions.
We find that RG specific expression of human MFN2 restores the proper number of LD levels and organelle contacts in Marf mutants whereas expression of human MFN1 (Dorn et al., 2011) does not, indicating that MFN2 specifically can rescue the defect in LD synthesis.
The proper number of background sequences of each of the CG-content bins is sampled.
