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Privately, though, the sanctions are a source of profound concern.
This matter is of profound concern to me and to other trustees.
That this subtle but fundamental inclusion is not manifest in our own parliament is of profound concern.
What happens in Greece is of profound concern to people there but the economy is not big enough to unseat the rest of the eurozone.
For Kadyrov, who has created a deeply personalized system of rule, support for ISIS inside Chechnya has become a matter of profound concern.
Nonetheless, high on the list of concerns the bishops raised during the meeting, Mr. Zwilling said, were two issues of profound concern to the church: same-sex marriage and abortion rights.
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Aren't you in the same territory as Michael Gove? A: I think I'm not in the same territory because I have a set of profound concerns with Michael Gove's approach to this.
So it is no surprise that both George W. Bush and John McCain have emphasized those principles for which our party in its best moments has stood and which are of such profound concern to religious conservatives.
The grave effects of internal emitters are of the most profound concern at Fukushima.
The introduction of the ABP has raised a number of questions that reflect a profound concern for issues of confidentiality and the responsibility of those in receipt of biological information to take action if and when information that may relate to the health of a competitor becomes apparent.
A model of healthy aging and profound concern for others, her wise counsel and energetic support will be greatly missed.
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com